http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2064930-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_51f318518efb5cac5b61814366cdf2d0 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-46 |
| filingDate | 1994-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1996-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e94c1862964ce8e625b419af03683832 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ef0c1b73198d2a8e771906b2a97824a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3168f928737a834137e929eede6cafc4 |
| publicationDate | 1996-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2064930-C1 |
| titleOfInvention | Method of synthesis of 5-[3(4)-r-1-adamantyl]-pyrimidines |
| abstract | FIELD: organic chemistry. SUBSTANCE: product: 5-[3(4)-R-1-adamantyl]-pyrimidines of the general formula where R 1 , R 2 - H, lower alkyl, phenyl substituted with CH 3 CF 3 , Cl-group; R 3 , R 4 , R 5 - H, hydroxy-, halide- or amino-group. Method involves interaction of hydroxyadamantanes with pyrimidine bases in trifluoroacetic acid at mole ratio hydroxyadamantane derivative : pyrimidine base : trifluoroacetic acid = 1:1: (6-10), at mixture boiling point. 1-Hydroxyadamantane and 3(4)-substituted 1-hydroxyadamantanes were used as hydroxyadamantane derivatives. 2,4-Dihydroxypyrimidine, or 2,4-dichloropyrimidine, or 2-amino-4,6-didihydroxypyrimidine were used as pyrimidine bases. Synthesized compounds can be used for synthesis of bioactive substances and in medicine. EFFECT: improved method of synthesis. |
| priorityDate | 1994-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.