| abstract |
FIELD: organic chemistry. SUBSTANCE: product: heterocyclic compounds of the formula (I) where R 1 , X, Y and B have the corresponding meanings, or their pharmaceutically acceptable additive acid salts, or heterocyclic compound N-oxide, or additive acid salt. These compounds were used in pharmaceutical compositions at concentration 0.5-730 mg per a dose. Synthesized compounds were used in medicine as antagonists of specific 5-hydroxytryptamine (5-HT) receptors for treatment patients with neuropsychiatric disorders. EFFECT: improved method of synthesis. |