| abstract |
FIELD: organic chemistry. SUBSTANCE: product: adducts of orotic acid with amino acids or amines of the formula (I) where NH 2 R beta-alanine residues, w -aminoenanthic acid, isoleucine methyl ester, D-glutamic acid, glutamic acid amide, asparagine, L-lysine, furfurylamine, 2-(3,4-dihydroxyphenyl)-ethylamine, guanidine, D-(-)-threo-p-nitrophenyl-2-aminopropanediol-1,3. Reagent 1: orotic acid. Reagent 2: β-alanine. Reaction conditions: temperature is below 80 C, stirring, cooling and crystallization. The yield is 69% of theory. Synthesized compounds were used in medicine, chemistry and agriculture. EFFECT: improved method of synthesis. 1 tbl |