| abstract |
FIELD: medicine as lipoxygenase inhibitor and in biosynthesis of interleinine-1. SUBSTANCE: the process comprises reacting the corresponding heteryl acid with a molar excess of 1,1-carbonyldiimidazole in an inert solvent and in an inert atmosphere and subsequently reacting the resulting product with a 3-substituted-2-oxoindol in the presence of an active agent at 0-50 C in an inert atmosphere and in an inert solvent. EFFECT: improved properties of the title compound. 4 tbl |