http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2034848-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f5152bf8b1b8998a379a1d54e94cd7fc |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-073 |
| filingDate | 1992-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1995-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c761240246fe91fbeb1c49bb1e11c38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f4a9484ea408c18dd6aeee838af2378 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74cf556a6d7a0d5123d6b265e8d41b22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66b1e581f2f72ba07228478e955d93ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d63e0a0f3e608efa3a7d9fac5b1c2a68 |
| publicationDate | 1995-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2034848-C1 |
| titleOfInvention | Method of azidothymidine synthesis |
| abstract | FIELD: organic chemistry. SUBSTANCE: product: 1-(3′-azido-2,3′-dihydroxy-D-erythro-pentofuranosyl)thymidine, yield is 50%. Content of basic substance is 97% . Reagent 1: 5′-O-benzoyl-2,3′-anhydroxythymidine. Reagent 2: sodium azide in the presence of lithium chloride and ammonium chloride at the ratio of all reagents 1:1-1.1:0.25-0.3:0.3:0.35, respectively, at 98-102 C following by treatment with methanol and diethylamine at the ratio 1:1. Preparation is used for AIDS treatment. EFFECT: improved method of synthesis. 3 cl, 1 tbl |
| priorityDate | 1992-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.