| abstract |
FIELD: organic chemistry. SUBSTANCE: product - 1,3-substituted sulfonylureas or their salts of formula (I) where X 1 and X 2 - H or Cl at condition that one of their is chlorine; A - radical of formula (II) or (III) where Z - S, O or NH; R 1 , R 2 , R 3 , R 4 - H, C 1 -C 3 -alkyl, C 1 -C 3 -alkoxy or C 1 -C 3 -alkylthio at condition that when A - radical of formula (III) then at least one of R 1 , R 2 , R 3 represents a substitute that is different from hydrogen. Synthesized compounds are used in medicine as antitumor agents. EFFECT: improved method of synthesis. 6 cl, 1 tbl |