http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2015150088-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2292 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate | 2015-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2015150088-A |
| titleOfInvention | Covalent monoconjugate of polysialic acid with thymosin beta 4, resistant to degradation in the blood stream, and method for its preparation |
| abstract | 1. Covalent monoconjugate of linear polysialic acid with thymosin beta 4, resistant to degradation in the blood stream. 2. A method for producing a polysialic acid monoconjugate with thymosin beta 4, comprising dissolving deacetylthymosin beta 4 in a multicomponent aqueous-organic buffer with a pH of 4.5, providing regioselective sialylation and containing sodium cyanoborohydride and a butyraldehyde derivative of polysialic acid, stirring thoroughly for 25 hours at 25 purification by RP-HPLC and lyophilization. |
| priorityDate | 2015-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.