http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2015119241-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 |
| filingDate | 2013-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2015119241-A |
| titleOfInvention | Acylaminocycloalkyl compounds suitable for the treatment of disorders that respond to the modulation of the dopamine D3 receptor |
| abstract | 1. The compound of formula I, where m is 1 or 2, n is 1 or 2, A is selected from the group consisting of CH, CHCH, CHFCH and CFCH, R is hydrogen or C-C alkyl, R is selected from the group consisting of hydrogen and fluoro, R is selected from the group consisting of hydrogen and methyl, R is selected from the group consisting of hydrogen and methyl, R is branched C-C1-6 alkyl or branched fluoro-substituted C-C1-6 alkyl, and R is oxygen containing a radical selected from the group consisting of C-C-alkoxy-CC-alkyl, fluoro-substituted C-C-alkoxy-CC-alkyl, hydroxy-CC-alkyl, fluoro-substituted hydroxy-CC-alkyl, ox ethanyl, fluoro substituted oxetanyl, oxolanyl, fluoro substituted oxolanyl, C-Cycloalkyl, fluoro-substituted C-Cycloalkyl, the cycloalkyl group in the last two mentioned radicals having 1 or 2 radicals selected from hydroxyl, CC-alkoxy and fluoro-substituted C and C-C-optional carry 1 or 2 radicals selected from C-C-alkyl and fluoro-substituted C-C-alkyl, C-Cycloalkoxy-CC-alkyl and fluoro-substituted C-Cycloalkoxy-CC-alkyl, and the cycloalkoxy in the last two mentioned radicals may carry 1 or 2 radicalsof hydroxyl, C-C-alkoxy, ftorzameschennogoC-C-alkoxy, C-C-alkyl and ftorzameschennogoC-C-alkyl, N-oxides, prodrugs and pharmaceutically acceptable salts of these soedineniy.2. A compound according to claim 1, wherein R is hydrogen or methyl. A compound according to claim 1, wherein R is methyl. A compound according to claim 1, wherein R is hydrogen. A compound according to claim 1, wherein R is hydrogen. The compound of claim 1, wherein m = 2.7. The compound of claim 1, wherein n = 2.8. A compound according to claim 1, in which both m and n = 1.9. A compound according to claim 1, wherein R and R are hydrogen. A compound according to claim 1, wherein either R is methyl and R is hydrogen, or R is hydrogen and R is methyl. 11. |
| priorityDate | 2012-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 394.