http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2015119159-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-282 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-248 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-24 |
| filingDate | 2013-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2015119159-A |
| titleOfInvention | ANTIBODIES TO INTERLEUKIN 6 AND THEIR APPLICATION |
| abstract | 1. The selected antibody that binds to human interleukin 6 (IL6), including: (a) the variable region of the heavy chain (V), which contains the hypervariable region of the heavy chain 1 (HC CDR1) having the sequence of SEQ ID NO: 2, hypervariable region heavy chain 2 (HC CDR2) having the sequence of SEQ ID NO: 4, a hypervariable region of heavy chain 3 (HC CDR3) having the sequence of SEQ ID NO: 6 or SEQ ID NO: 16; or (b) the variable region of the light chain (V), which contains the hypervariable region of light chain 1 (LC CDR1) having the sequence of SEQ ID NO: 9, the hypervariable region of light chain 2 (LC CDR2) having the sequence of SEQ ID NO: 11, and a light chain hypervariable region 3 (LC CDR3) having the sequence of SEQ ID NO: 13 or SEQ ID NO: 15.2. The selected antibody according to claim 1, which contains (i) V, which contains HC CDR1 having the sequence of SEQ ID NO: 2, HC CDR2 having the sequence of SEQ ID NO: 4, and HC CDR3 with the sequence of SEQ ID NO: 6; or (ii) V which contains HC CDR1 having the sequence of SEQ ID NO: 2, HC CDR2 having the sequence of SEQ ID NO: 4, and HC CDR3 having the sequence of SEQ ID NO: 16.3. The isolated antibody according to claim 2, which contains V containing the amino acid sequence of SEQ ID NO: 17 or SEQ ID NO: 18.4. The isolated antibody according to claim 2 or 3, which further comprises (i) V, which contains LC CDR1 having the sequence of SEQ ID NO: 9, LC CDR2 having the sequence of SEQ ID NO: 11, and LC CDR3 having the sequence of SEQ ID NO : 13; or (ii) V, which contains LC CDR1 having the sequence of SEQ ID NO: 9, LC CDR2 having the sequence of SEQ ID NO: 11, and LC CDR3 having the sequence of SEQ ID NO: 15.5. The isolated antibody according to claim 4, which contains V containing the amino acid sequence of SEQ ID NO: 19 or SEQ ID NO: 20.6. The isolated antibody according to claim 1, which is selected from the group consisting of: (i) an antibody containing V that contains HC CDR1 having the sequence of SEQ ID NO: 2, HC CDR2 having the sequence of SEQ ID NO: 4, and HC CDR3 , |
| priorityDate | 2012-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 108.