http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2015115970-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 |
| filingDate | 2013-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2015115970-A |
| titleOfInvention | NEW COMPOUNDS THAT ARE ERK INHIBITORS |
| abstract | 1. The compound of the formula: or a pharmaceutically acceptable salt, ester, solvate or prodrug thereof, wherein: R is —NRR; R is selected from the group consisting of: H, (CC) aryl- (C-C1-6 alkyl) heterocycloalkyl-, - (C- Calkyl), - (C-Calkyl) -O- (C-Calkyl), - (C-Calkyl) heterocycloalkyl- (C-Caryl), - (C-Calkyl) (CC) aryl, - (C-Calkyl) heteroaryl , - (C-Cycloalkyl) - (C-Caryl), -heterocycloalkyl- (C-Caryl), - (C-Ci-alkyl) - (C-Ci-cycloalkyl), -CH (C-Ci-alkyl) (C-Ci-cycloalkyl), - CH (C-Caryl) ((C-Calkyl) N (R)), -CH (C-Caryl) (heterocycloalkyl), - (C-Cicycloalkyl-O- (C-Calkyl)), -CH (C-Caryl ) C (O) N (R), where each R is independently selected, and is fused (heterocycloal keel) (CC) aryl, wherein said heterocycloalkyl is a 5-8 membered ring (including two atoms shared by said aryl) containing 1-3 heteroatoms selected from the group consisting of: O, S and N, and where the remaining atoms are carbon; and wherein said aryl, heterocycloalkyl, heteroaryl and cycloalkyl groups of said R groups are optionally substituted with 1-3 substituents independently selected from the group consisting of: CN, halogen, —O- (C — C1-6 alkyl), —OH, -CF, - (C-Ci-alkyl), -O (halogen-substituted (C-Ci-alkyl)), -N (R), aryl and heteroaryl; and where the indicated alkyl groups are the aforementioned R groups are optionally substituted with 1 to 3 substituents independently selected from the group consisting of: CN, halogen, —O— (C-Calkyl), —OH and —CF, —O (halogen-substituted (C-Calkyl)) and - S (C-C1-6 alkyl); each R, and R is independently selected from the group consisting of: H, - (C-C1-6 alkyl), - (C-C1-6 alkyl) -O- (C-C1-6 alkyl), -C (O) R, -S (O) R, - (C-C1-6 alkyl), substituted with 1-3 substituents independently selected from the group consisting of: halogen, -OH and -S (O) (C1-6alkyl), - (C1-6 cycloalkyl) , - (C-Cicycloalkyl) substituted by 1-3 substituents independently selected from the group consisting of: halogen, - (C-Calkyl), -NH, -NH (C-Calkyl), -N (C-Calkyl), where every alc l is independently selected, - (C-Cicycloalkenyl), - (C-Coxocycloalkenyl), - (C-Caryl), - (C-Caryl), substituted with 1-3 substituents independently selected from the group consisting of: -CN, - O (C-C1-6 alkyl) and halogen, |
| priorityDate | 2012-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.