http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2015113348-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6408 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate | 2013-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2015113348-A |
| titleOfInvention | CELLING PEPTIDES IN CELLS BINDING INTERFERON-REGULATING FACTOR 5 |
| abstract | 1. A peptide penetrating into the cell that binds the regulatory factor of interferon IRF5 (CPP-IRF5), where the peptide contains an amino acid sequence of 20 to 40 amino acids in length, and where the specified amino acid sequence additionally contains, in particular, an amino acid sequence motif selected from the group consisting of: a) IxLxISxPxxK (SEQ ID No. 25), where I is isoleucine, L is leucine, S is serine, P is proline, K is lysine, and ax is independently selected from among all amines acids; or b) Y-R1-R2-R3-R8-R4-R5-R9 (SEQ ID No. 24), where Y is tyrosine, R1 is an amino acid selected from the group of tryptophan (W) or alanine (A), R2 is an amino acid selected from the group consisting of leucine (L) or threonine (T), R3 is an amino acid selected from the group consisting of leucine (L), alanine (A), aspartic acid (D), phenylalanine (F) or tyrosine (Y), R8 is leucine (L), R4 is an amino acid selected from the group consisting of leucine (L), glycine (G) or threonine (T), R5 is minokislotu selected from the group consisting of phenylalanine (F), leucine (L) or methionine (M), R 9 represents valine (V) or leucine (L); or c) KD-R6-MV-R7-FKD (SEQ ID NO: 2), where K is lysine, D is aspartic acid, R6 is an amino acid selected from the group consisting of leucine and aspartic acid, M is methionine, R7 is selected from the group consisting of glutamine-tryptophan (QW) and arginine-phenylalanine (RF), and F is phenylalanine; or its pharmaceutically acceptable salts. 2. The CPP-IRF5 peptide according to claim 1, which contains an amino acid sequence of 20 to 40 amino acids in length, where specified |
| priorityDate | 2012-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.