http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2015106683-A
Outgoing Links
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|---|---|
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| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-186 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1808 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L26-0066 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 |
| filingDate | 2013-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2015106683-A |
| titleOfInvention | VESICULES CONTAINING EPIDERMAL GROWTH FACTOR AND ITS COMPOSITIONS |
| abstract | 1. Vesicles containing epidermal growth factor (EGF), cationic surfactant and cholesterol or its derivatives. 2. The vesicles of claim 1, wherein the cationic surfactant is a quaternary ammonium type substance. The vesicles of claim 2, wherein the cationic quaternary ammonium type surfactant is a surfactant selected from the group consisting of cetyltrimethylammonium bromide (CTAB), cetrimide and benzalkonium chloride (BKC). 4. Vesicles according to paragraphs. 1-3, where the molar ratio between cationic surfactant and cholesterol or its derivatives is in the range of 10M: 1Μ to 1M: 5M and the molar ratio between EGF and cholesterol or its derivatives is in the range of 0.5 μM: 1Μ up to 100 μM: 1M. 5. The vesicles of claim 1, which are characterized in that they have a single layer structure and an approximate average size between 25 and 500 nm, preferably between 50 and 300 nm. The vesicles of claim 1, wherein the EGF is included in the vesicular bilayer. The vesicles according to claim 1, which are obtained by compressed fluid technology (CF). The vesicles of claim 7, wherein the CF technology includes a method comprising: a) preparing an aqueous solution of EGF and a cationic surfactant, b) dissolving cholesterol or its derivatives in an organic solvent expanded with CF, c) synthesizing the vesicles by pressure relief a solution obtained from step b) to a solution obtained from step a) .9. The vesicle of claim 8, wherein the cationic surfactant is a quaternary ammonium type substance. A method of producing vesicles containing EGF, a cationic surfactant and cholesterol or its derivatives, characterized by the content of the following: a) preparation |
| priorityDate | 2012-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.