http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2015102057-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4353 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 |
| filingDate | 2013-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2015102057-A |
| titleOfInvention | NEW CONDENSED PYRIDINE DERIVATIVES APPLICABLE AS c-MET TYROSINKINASE INHIBITORS |
| abstract | 1. The compound of formula I or a pharmaceutically acceptable salt, solvate, chelate, non-covalent complex or prodrug thereof, wherein B is absent, is O, S, OCH or SCH; each of R, R, R and R is independently hydrogen, halogen, substituted or unsubstituted C1-6alkyl, substituted or unsubstituted C1-6alkenyl, substituted or unsubstituted C1-6nalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heterocyclyl, alkanoyl, (alkoxy) carbonyl, C1-6alkylsulfinyl, C1-6alkylsulfonyl, arylsulfonyl, -1C -NO, hydroxy, amino, carboxy, oxo, carbamoyl, Calkoxy, Calkenyloxy, Calkynyloxy, Calkylthio, N- (Calkyl) carbamoyl, N, N-di (Calkyl) carbamoyl, Calkanoyloxy, Calkanoylamino, Calkynoylamino, N- (Camoalkyl) or N, N-di (C1-6alkyl) sulfamoyl; or R and R together or R and R together form = O or cyclopropyl; A is N or CH; n is 0, 1, 2 or 3; each R is independently halogen, substituted or unsubstituted C1-6 alkyl, —CN, —NO, —OR, —N (R), —S (O) R or —C (O) R; each R independently is hydrogen or substituted or unsubstituted C1-6 alkyl; Z is NHR or is represented by formula II, wherein each of R and R is independently hydrogen, substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted ari , substituted or unsubstituted heteroaryl, substituted or unsubstituted heterocyclyl, Calkanoyl, (Calkoxy) carbonyl, Calkylsulfinyl, Calkylsulfonyl or arylsulfonyl; R is represented by the formula III, IV, V, VI or VII, where B represents, where each Q is independently; B is NHQ, and Q is substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, |
| priorityDate | 2012-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 142.