http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2015101230-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate | 2013-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2015101230-A |
| titleOfInvention | COMPOSITIONS AND METHODS FOR INHIBITING MASP-1, AND / OR MASP-2, AND / OR ASP-3 FOR TREATING VARIOUS DISEASES AND DISORDERS |
| abstract | 1. A method of inhibiting MASP-3-dependent complement activation in an individual suffering from or at risk of developing a disease or disorder selected from the group consisting of age-related macular degeneration, arthritis, disseminated intravascular coagulation, thrombotic microangiopathy, asthma, dense deposit disease, low-immune necrotizing glomerulonephritis with half moons, traumatic brain damage, aspiration pneumonia, endophthalmitis, optic neuromyelitis or Bech disease an even comprising administering to the individual a composition containing an amount of an MASP-3 inhibiting agent effective to inhibit MASP-3 dependent complement activation. 2. The method of claim 1, wherein the MASP-3 inhibitor is a monoclonal anti-MASP-3 antibody or fragment thereof that specifically binds to part of SEQ ID NO: 8.3. The method of claim 1, further comprising administering to the individual a composition comprising a MASP-1.4 inhibitory agent. The method of claim 3, wherein the MASP-1 inhibitor is a monoclonal anti-MASP-1 antibody or fragment thereof that specifically binds to part of SEQ ID NO: 10.5. The method of claim 1, further comprising administering to the individual a composition comprising a MASP-2.6 inhibitory agent. The method of claim 5, wherein the MASP-2 inhibitor is a monoclonal anti-MASP-2 antibody or fragment thereof that specifically binds to part of SEQ ID NO: 5.7. The method of claim 1, further comprising administering to the individual a composition comprising a MASP-1 inhibitory agent and a MASP-2.8 inhibitory agent. The method of claim 1, wherein the MASP-3 inhibitory agent inhibits alternatively triggered accumulation of C3b. The method of claim 1, wherein the MASP-3 inhibitory agent inhibits |
| priorityDate | 2012-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.