http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2015100531-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-44 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57 |
| filingDate | 2013-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2015100531-A |
| titleOfInvention | Capsules with Soluble Estradiol for Intravaginal Administration |
| abstract | 1. An encapsulated pharmaceutical composition for intravaginal administration, comprising: a) a therapeutically effective amount of soluble estradiol; and b) a dissolving agent, wherein the dissolving agent is at least one of C6-C12 fatty acids, glycol and their monoglyceride, diglyceride or triglyceride, wherein the pharmaceutical composition does not contain a hydrophilic gel-forming bioadhesive agent. 2. The composition according to claim 1, wherein the composition contains from about 1 microgram to about 25 micrograms of estradiol. 3. The composition according to claim 2, wherein the composition contains from about 1 microgram to about 10 micrograms of estradiol. The composition according to any one of paragraphs. 1-3, in which the composition is encapsulated in a gelatin capsule. 5. The composition of claim 4, wherein the capsule is a soft gelatin capsule. The composition according to paragraphs. 1-3, in which the dissolving agent is at least one of the following: caproic fatty acid ester, caprylic fatty acid ester, capric fatty acid ester, and combinations thereof. The composition according to paragraphs. 1-3 or 5, wherein the dissolving agent is a monoglyceride, diglyceride or triglyceride of at least one C6-C12 fatty acid. The composition according to paragraphs. 1-3 or 5, wherein the dissolving agent is caprylic / capric triglyceride. 9. The composition according to paragraphs. 1-3 or 5, in which the dissolving agent is preferably at least one of C6-C12 fatty acids, glycol and their monoglyceride, diglyceride or triglyceride. 10. The composition of claim 1, wherein the composition further comprises a nonionic surfactant. The composition of claim 10, wherein the nonionic surfactant contains a polyethylene glycol ether and a fatty acid ester. The composition of claim 10, wherein the nonionic surfactant |
| priorityDate | 2012-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.