http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2014148305-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-10 |
| filingDate | 2013-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2014148305-A |
| titleOfInvention | Camsylate salt |
| abstract | 1. Camsylate salt of (1r, 1′R, 4R) -4-methoxy-5 ″ -methyl-6 ′ - [5- (prop-1-yn-1-yl) pyridin-3-yl] -3′H -dispiro [cyclohexane-1,2′-inden-1′2′-imidazole] -4 ″ -amine. 2. Camsylate salt of (1r, 1′R, 4R) -4-methoxy-5 ″ -methyl-6 ′ - [5- (prop-1-yn-1-yl) pyridin-3-yl] -3′H-dispiro [cyclohexane-1,2′-inden-1′2′-imidazole] -4 ″ -amine, characterized in that it gives a powder X-ray diffraction (X-ray diffraction) pattern showing substantially very strong (vs), strong ( s) and average (m) peaks with d-values: 3. Camsylate salt of (1r, 1′R, 4R) -4-methoxy-5 ″ -methyl-6 ′ - [5- (prop-1-yn-1-yl) pyridin-3-yl] -3′H-dispiro [cyclohexane-1,2′-inden-1′2′-imidazole] -4 ″ -amine, characterized in that it gives a powder X-ray diffraction pattern substantially the same as that shown in FIG. 1.4. A pharmaceutical composition comprising, as an active ingredient, a therapeutically effective amount of a salt according to claim 1, 2 or 3, together with at least one pharmaceutically acceptable excipient, carrier or diluent. 5. Salt according to claim 1, 2 or 3 for use as a medicine. 6. The salt of claim 5 for use as a medicament for the treatment or prevention of pathology related to Aβ (amyloid β-peptide). The salt of claim 6 for use as a medicament for the treatment or prevention of Aβ-related pathology, wherein said Aβ-related pathology is Down syndrome, β-amyloid angiopathy, cerebral amyloid angiopathy, hereditary cerebral hemorrhage, a disorder associated with cognitive impairment, MCI ("mild cognitive impairment"), Alzheimer's disease, memory loss, attention deficit symptoms associated with Alzheimer's disease, neurodegeneration associated with Alz disease gamers |
| priorityDate | 2012-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.