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filingDate 2014-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2016-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2014146985-A
titleOfInvention NEW MEDICINES FOR LOCAL USE ON THE BASIS OF SULPHATED HYALURONIC ACID AS STIMULATORS OR INHIBITORS OF CYTOKINE ACTIVITY
abstract 1. Sulfated hyaluronic acid for topical use as a stimulator of skin absorption of pharmacologically and / or biologically active agents, and the specified sulfated hyaluronic acid (HA) has a molecular weight of from 10,000 to 50,000, from 150,000 to 250,000 or from 500,000 to 750,000 Yes, and the degree of sulfation 1 or 3.2. A topical pharmaceutical composition containing sulfated hyaluronic acid according to claim 1, possibly together with pharmacologically and / or biologically active agents. The pharmaceutical composition according to claim 2, containing steroids, hormones, proteins, trophic factors, vitamins, non-steroidal anti-inflammatory drugs, topical chemotherapeutic drugs, antibiotics, antiviral agents, local anesthetics, anticoagulants and / or fibrinolytic agents, enzymes and / or other proteases. 4. The pharmaceutical composition of claim 3, comprising hyaluronidase. The pharmaceutical composition of claim 5, further comprising polymers such as hyaluronic acid and its derivatives, carboxymethyl cellulose and / or other polymers of natural or synthetic origin. The pharmaceutical composition according to PP. 2-5 in the form of ointment, lipogel, hydrogel, lipstick, cream, plasters, vaginal suppositories and suppositories, foam, gel for application to mucous membranes, ophthalmic preparations, formulations for washing the vagina, rinsing for the oral cavity, solutions for local application or inhalation. 7. The pharmaceutical composition of claim 6 in the form of patches containing sulfated hyaluronic acid in combination with non-steroidal anti-inflammatory drugs
priorityDate 2009-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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