http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2014139705-A
Outgoing Links
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
filingDate | 2013-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2014139705-A |
titleOfInvention | Pyrazolotriazine derivatives as selective inhibitors of cyclin-dependent kinases |
abstract | 1. The compound of General formula (I) in which R represents H or-CH; R represents-R, -QR, -R, -Q- (CH) -R, - (CH) -R, - (CH) -NH -R, - (CH) -NH- (CH) -R, -CO-NH- (CH) -NH, -CO-NH- (CH) -R, -CO-R, -SO-R, - ( CH) -NR-R, - (CH) -NR- (CH) -R, -CO-NR- (CH) -R, - (CH) - (Q) - (CH) - (G) - (CH ) - (G) - (CH) -R, - (Q) - (CH) - (G) - (CH) -R, - (Q) - (CH) - (G) - (CH) -R, - (CH) - (Q) - (CH) - (G) - (CH) - (G) -CH-R, -QR, -Q-CH (COOR) -R, -Q-CH (R) - R, - (CH) -OH, -CHO, -OH; R is -OH, -NH, -F, -Cl, -Br, -I, -CN, -OR, -R, -CO-OR, - NR-CO-OR, -NHR, -NRR, -CONRR, -O-CO-NRR, -O-CO-OR, -CH, -NR-CO-NRR, -SONRR, -C (= NR) -NRR , -C (R) = NR, -N = CRR, -N = S (= O) RR, -CRRR, -CR = CRR, -C≡CR, -NR-C (= NR) -NRR, -SR , -S (= O) R, -NR-S (= O) R, -OS (= O) R, -SO-R, -NR-SO-R, -O-SO-R, -SO (= NR) -R, -CO-R, -O-CO-R, -NR-CO-R, -CHF, -CHF, -CF, 3-membered heterocyclyl, 4-membered heterocyclyl, 5-membered heterocyclyl, 6- member getter cyclic, monounsaturated 4-membered heterocyclyl, monounsaturated 5-membered heterocyclyl, monounsaturated 6-membered heterocyclyl, 3-membered carbocyclyl, 4-membered carbocyclyl, 5-membered carbocyclyl, 6-membered carbocyclyl, 6-membered a 6-membered heteroaryl, where all the above cyclic systems can be substituted with 1-4 substituents selected from Z, Z, Z and Z; Z and Z, if they are attached to the same carbon atom, can together be an atom = O, which forms a carbonyl group with a carbon atom, to which together with Z and Z; R together with R can form a carbocyclic or heterocyclic 4-, 5-, 6- or 7-membered ring with two carbon atoms of the benzene ring to which R and R are attached, and the specified 4-, 5-, 6- or 7 the membered ring may be partially saturated or unsaturated and may be substituted by 1-4 substituents selected from Z, Z, Z and Z; Z and Z, if they are attached to the same carbon atom, can together be an atom = O, which forms a carbonyl group with a carbon atom to which Z and Z are attached; R-R is independent of each other ygs are —H, —F, —Cl, —CH; R is - (CH) —NH, - (CH) —N (RR), carbocyclyl, heterocyclyl, spirocarbocyclyl, spiroheterocyclyl, wherein the above carbocyclyl, heterocyclyl, spirocarbocyclic and spiroheterocyclyl residues are connected via a carbon atom of the ring and can be substituted by 1-3 substituents, in |
priorityDate | 2012-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 652.