http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2014124974-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
| filingDate | 2012-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2014124974-A |
| titleOfInvention | PHOTOACTIVE CHEMICAL DISCOLORING OF DYES |
| abstract | 1. A method for sensing multiple targets in a biological sample, comprising: (a) binding at least one probe to one or more than one target present in a biological sample containing multiple targets; (b) detecting a signal from at least one probe, bound in step (a); (c) bringing the sample containing the bound probe from step (a) into contact with the electron transfer reagent; (d) irradiating the sample from step (c); (e) binding of at least one probe to one or more than one target, present s in the sample of step (g); and (e) detecting a signal from a probe coupled in step (e). 2. The method of claim 1, wherein the probe in step (a) comprises an optical signal generator, and the signal observed in step (b) is an optical signal. The method of claim 2, wherein the probe in step (a) comprises a fluorescent signal generator, and the signal observed in step (b) is a fluorescent signal. The method of claim 1, wherein irradiating the sample in step (d) is carried out in the presence of a buffer at pH 5-9.5. The method of claim 1, wherein irradiating the sample in step (d) is carried out by exposing the sample to light with a wavelength of 350 nm to 1.3 μm. The method of claim 5, wherein irradiating the sample in step (d) is carried out by exposing the sample to light with a wavelength of 400-700 nm. The method of claim 1, wherein the electron transfer reagent is a borate salt represented by the following structural formula: wherein each of R, R, and R is independently alkyl, alkenyl, alkynyl, aryl, or heteroaryl, wherein said alkyl, alkenyl, alkynyl, aryl, or heteroaryl optionally substituted with one or more substituents selected from the group consisting of (C — C) alkyl, (CC) alkoxy, (CC) alkylamino, |
| priorityDate | 2011-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.