http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2014124531-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-04 |
| filingDate | 2013-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2014124531-A |
| titleOfInvention | (1R, 4R) 7-OXO-2-AZABICYCLO [2.2.2] OCT-5-EH AND ITS DERIVATIVES |
| abstract | 1. The compound of Formula (I) or (Ia): or a salt of said compound, wherein R is selected from the group consisting of hydrogen, —COR, —COR, —C (R) and a protecting group for the amine; R is selected from the group consisting of C— C1-6alkyl, optionally substituted with 1-3 substituents selected from Ci-Caryl, Ci-Ci-cycloalkyl, Ci-Ci heteroaryl, Ci-Ci heterocyclyl, halogen, amino, -N, hydroxy, Ci-Cialkoxy, silyl, nitro, cyano and the COH group or its ester group, C-Calkenyl, C-Calkynyl, C-Caryl, C-C heteroaryl, C-Ccycloalkyl and C-C heterocyclyl, R and R are independently selected from the group consisting of hydrogen, C-Calkyl, optionally 1 to 3 substituents selected from C-Caryl, C-Ccycloalkyl, C-C heteroaryl, C-C heterocyclyl, halogen, amino, -N, hydroxy, C-Calkoxy, silyl, nitro, cyano and the COH group or its ester group, C-Calkenyl, C-Calkynyl, C-Caryl, C-C heteroaryl, C-Ccycloalkyl and C-C heterocyclyl, R and R are independently hydrogen, hydroxy, C-Calkyl, C-Calkenyl and C-Calkynyl, -SR or -OR, wherein the specified alkyl, alkenyl or alkynyl group is optionally substituted by 1-3 substituents selected from the group consisting of keto, halogen, C-alkoxy, amino, hydroxy, cyan , nitro, —NHCOCH, —N and the —COH group or its ester group, provided that at least one of R and R, preferably R, is a substituent other than hydrogen, or R and R together with the carbon atom to which they are attached form a ketone (C = O) group, Schiff base (= NR), vinylidene moiety of the formula = CRR, or form a 5-6 membered cyclic ketal or thioketal, wherein the cyclic ketal or thioketal has the formula: each R is independently selected from the group consisting of C- C1-6alkyl optionally substituted with 1 to 3 substituents selected from C-Caryl, C -Cycloalkyl, C-C heteroaryl, C-C heterocyclyl, halogen, amino, -N, hydroxy, C-alkoxy, silyl, nitro, cyano and the COH group or e |
| priorityDate | 2012-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.