http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2014120373-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-397 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2012-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2014120373-A |
| titleOfInvention | COMPOUNDS OF AZETIDINE AND THEIR APPLICATION AS INHIBITORS OF SOLUBLE EPOXYHYDROLASE |
| abstract | 1. The compound of formula I: where A is selected from the group consisting of Ia, Ib or Ic: where X is N or CH; Y is NH or CH; LiboX is NH or CH; Y is N or CH; or where L is a bond, - (CH) -, -NH- (CH) -C (O) -, - (CH) -C (O) -, - (CH) -SO- or - (CH) -NR-C (O) -; L is a bond, - (CH) -, - (CH) -C (O) -NH-, -NH- (CH) -C (O) -NH-, - (CH) -C ( O) -, - (CH) -SO - or - (CH) -NR-C (O) -; R is phenyl, 5- or 6-membered heteroaryl, adamantyl or - (CH) -phenyl, where such phenyl is, heteroaryl or adamantyl is unsubstituted or substituted with R in an amount of one to three; R is phenyl, 5- or 6-membered heteroaryl or - (CH) -phenyl, where such phenyl or heteroaryl is unsubstituted or substituted with R in an amount of from one to three; R represents a hydrogen atom or higher alkyl; R represents a hydrogen atom or lower alkyl; R represents a halogen atom, lower alkyl, lower haloalkyl, lower haloalkoxy or —C (O) OR, or stereoisomers, tautomers or pharmaceutically acceptable salts thereof except (4-bromophenyl) [6- [(4-methylphenyl) sulfonyl] -1,6-diazaspiro [3,3] hept-1-yl] methanone, 6 - [(4-methylphenyl) sulfonyl] -1- (phenylmethyl) -1,6-diazaspiro [ 3,3] heptane, 2,6-bis [(4-methylphenyl) sulfonyl] -2,6-diazaspiro [3,3] heptane and 2-phenyl-6- (phenylmethyl) -2,6-diazaspiro [3, 3] heptane, provided that when L is —C (O) —NH—, L is not tsya -CH-, with the proviso that when Lpredstavlyaet -CH-, L is not a bond, provided that when a Lpredstavlyaet -SO-, L is not is -CH-, and with the proviso that L and Lyavlyayutsya razlichnymi.2. A compound according to claim 1, selected from the group consisting of the following compounds: 6-benzoyl-2,6-diazaspiro [3.3] heptane-2-carboxylic acid 2,4-dichlorobenzylamide; 4- [6- (2,4-dichlorobenzyl) � |
| priorityDate | 2011-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.