http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2014120166-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535 |
| filingDate | 2012-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2014120166-A |
| titleOfInvention | SUBSTITUTED Bicyclic AZA-HETEROCYCLES AND THEIR ANALOGUES AS SIRTUIN MODULATORS |
| abstract | 1. The compound represented by structural formula (I): where one of D and E represents N and the other represents C; where D is N, one of A and B is N, and the other is CR; when E is N, B is N and A is N or CR; or a salt thereof, where: each R is independently selected from hydrogen, halogen, OH, C≡N, C-Ci-alkyl, halogen-substituted C-Ci-alkyl, C- Alkoxy substituted C 1-6 alkyl, hydroxy substituted C 1-6 alkyl, OR, O- (C 1-6 alkyl) -OR, S- (C 1-6 alkyl), S- (halogen substituted 1-4C-alkyl), N (hydroxy substituted C 1-6 alkyl), N (methoxy substituted C-C1-6 alkyl), N (C-C1-6 alkyl) - (hydroxy-substituted C-C1-6 alkyl), N (C-C1-6 alkyl) (methoxy-substituted C-C1-6 alkyl), N (hydroxy-substituted 1-4C-alkyl) (methoxy-substituted 1-4C-alkyl), 1-4C-cycloalkyl and 4-8 membered non-aromatic heterocycle, and when one or both of E and A are N, then R may be further selected from halogen-substituted methyl and C-Cycloalkyl; R is an aromatic heterocycle or a fused carbocycle, where R is optionally substituted with one or more substituents independently selected from halogen , C≡N, C-Ci-alkyl, halogen-substituted C-Ci-alkyl, C-Ci-alkoxy-substituted Ci-Ci-alkyl, hydroxy-substituted Ci-Ci-alkyl, OR, O- (Ci-Ci-alkyl) -OR, = O, Ci-Cycloalkyl, SOR, SR, ( C-Calkyl) -N (R) (R), N (R) (R), O- (C-Calkyl) -N (R) (R), O- (C-Calkyl) -CRR (C-Calkyl ), (C-C1-6 alkyl) -O- (C-C1-6 alkyl) -N (R) (R), C (= O ) -N (R) (R), (C-Calkyl) -C (= O) -N (R) (R), O- (C-Calkyl) -CRR- (C-Calkyl), CRR, phenyl, O-phenyl, second heterocycle, O- (second heterocycle), 3,4-methylenedioxy, halogen-substituted 3,4-methylenedioxy, 3,4-ethylenedioxy and halogen-substituted 3,4-ethylenedioxy, where any phenyl, saturated heterocycle or second heterocyclic substituent in R is optionally substituted with one or more |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2799332-C2 |
| priorityDate | 2011-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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