http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2014119254-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 |
| filingDate | 2012-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2014119254-A |
| titleOfInvention | Apoptosis inducing agents for the treatment of malignant neoplasms and immune and autoimmune diseases |
| abstract | 1. A compound having the formula (I) Formula (I), or a therapeutically acceptable salt thereof, wherein X is heteroaryl; wherein the heteroaryl represented by X is optionally substituted with one, two, three or four R; Y is phenylene or C heteroarylene; optionally fused with one or two rings selected from the group consisting of Cycloalkane, Cycloalkene, benzene, Ceteroarene, Ceterocycloalkane and Ceterocycloalkene; where Y is optionally substituted with one, two, three or four substituents independently selected from the group consisting of R, OR, SR, S (O) R, SOR, C (O) R, CO (O) R, OC (O) R , OC (O) OR, NH, NHR, N (R), NHC (O) R, NRC (O) R, NHS (O) R, NRS (O) R, NHC (O) OR, NRC (O) OR, NHC (O) NH, NHC (O) NHR, NHC (O) N (R), NRC (O) NHR, NRC (O) N (R), C (O) NH, C (O) NHR, C (O) N (R), C (O) NHOH, C (O) NHOR, C (O) NHSOR, C (O) NRSOR, SONH, SONHR, SON (R), CO (O) H, C ( O) H, OH, CN, N, NO, F, Cl, Br and I; L is selected from the group consisting of (CRR), (CRR) -O- (CRR), (CRR) -C (O) - ( CRR), (CRR) -S- (CRR), (CRR) -S (O) - (CRR), (CRR) -NRC (O) - (CRR), (CRR) -C (O) NR- ( CRR), (CRR) -NR- (CRR), (CRR) -S (O) NR- (CRR) and (CRR) -NRS (O) - (CRR); and Y is selected from the group consisting of branched chain C1-6 alkyl, cycloalkyl, cycloalkenyl, phenyl and heterocyclyl; where Cycloalkyl, Cycloalkenyl, phenyl and Ceterocyclyl are optionally fused to one or two rings selected from the group consisting of Ccycloalkane, Ccycloalken, benzene, Ceteroarene, Ceterocycloalkane and Ceterocycloalken; where Y is optionally substituted with one, two, three, four or five substituents independently selected from the group consisting of R, OR, SR, S (O) R, SOR, C (O) R, CO (O) R, OC (O ) R, OC (O) OR, NH, NHR, N (R), NHC (O) R, NRC (O) R, NHS (O) R, NRS (O) R, NHC (O) OR, NRC ( O) OR, NHC (O) NH, NHC (O) NHR, NHC (O) N (R), NRC (O) NHR, NRC (O) N (R), C (O) NH, C (O) NHR, C (O) N (R), C (O) NHOH, C (O) NHOR, C (O) NHSOR, C (O) NRSOR, SONH, SONHR, SON (R), CO (O) H, C (O) H, OH, CN, N, NO, F, Cl, Br and I; or L is a bond; and Y is selected from the group consisting of Cycloalkyl, Cycloalkenyl, phenyl and Ceterocyclyl; where is the cycle |
| priorityDate | 2011-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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