http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2014118727-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16134 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-36143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16734 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-25 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-245 |
| filingDate | 2012-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2014118727-A |
| titleOfInvention | RECOMBINANT SELF-REPLICING POLYCISTRON RNA MOLECULES |
| abstract | 1. A self-replicating RNA molecule containing a polynucleotide that contains: a) a first nucleotide sequence encoding a first protein or fragment thereof, operably linked to a first subgenomic promoter (SGP); and b) a second nucleotide sequence encoding a second protein or fragment thereof operably linked to a second SGP; c) a third nucleotide sequence encoding a third protein or fragment thereof operably linked to a third SGP; and d) a fourth nucleotide sequence encoding a fourth protein or fragment thereof operably linked to a fourth SGP; wherein, when a self-replicating RNA molecule is introduced into a suitable cell, the first, second, third and fourth proteins or fragments thereof are produced. The self-replicating RNA molecule according to claim 1, provided that the first protein, second protein, third protein and fourth protein are not the same protein or fragments of the same protein, the first protein is not a fragment of the second, third or fourth protein, the second the protein is not a fragment of the first, third or fourth protein, the third protein is not a fragment of the first, second or fourth protein and the fourth protein is not a fragment of the first, second or third protein. 3. A self-replicating RNA molecule according to claim 1 or 2, further comprising a fifth nucleotide sequence encoding a fifth protein or fragment thereof operably linked to a fifth SGP. 4. The self-replicating RNA molecule according to claim 1, characterized in that the first protein or its fragment, the second protein or its fragment, the third protein or its fragment and the fourth protein or its fragment and, if |
| priorityDate | 2011-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419512635 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID962 |
Total number of triples: 20.