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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-22
filingDate 2012-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2015-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2014109747-A
titleOfInvention MORPHOLIN-SUBSTITUTED UREA OR CARBAMATE DERIVATIVES AS MTOR INHIBITORS
abstract 1. The compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein m is 1 or 2; n is 1; 2; 3 or 4; each R is independently selected from the group consisting of H; halogen; CN; C (O) OR; OR; oxo (= O); C (O) R; C (O) N (RR); S (O) N (RR); S (O) N (RR); S (O) R; S (O) R; N (R) S (O) N (RR); N (R) S (O) N (RR); SR; N (RR); NO; OC (O) R; N (R) C (O) R; N (R) S (O) R; N (R) S (O) R; N (R) C (O) N (RR); N (R) C (O) OR; OC (O) N (RR) and C1-6alkyl, where C1-6alkyl is optionally substituted with one or more R, which are the same or different; possibly two Rs are joined together with the ring to which they are attached to form an 8-11 membered heterobicycle; R, R , R are independently selected from the group consisting of H; C 1-6 alkyl, wherein C 1-6 alkyl is optionally substituted by one or more halogen atoms that are the same or different; R 1 represents halogen; CN; C (O) OR; OR; C (O) R; C (O) N (RR); S (O) N (RR); S (O) N (RR); S (O) R; S (O) R; N (R) S (O) N (RR); N (R) S (O) N (RR); SR; N (RR); NO; OC (O) R; N (R) C (O) R; N (R) S (O) R; N (R) S (O) R; N (R) C (O) N (RR); N (R) C (O) OR or OC (O) N (RR); R, R, R are independently selected from the group consisting of H and C 1-6 alkyl, where C 1-6 alkyl is optionally substituted with one or more halogen atoms that are the same or different; T represents represents phenyl or a 5-6 membered aromatic heterocycle, where T is substituted by a group N (R) C (O) N (RR) or N (R) C (O) OR and optionally further substituted by one or more R, which are the same or different; R is halogen; CN; C (O) OR; OR; C (O) R; C (O) N (RR); S (O) N (RR); S (O) N (RR); S (O) R; S (O) R; N (R) S (O) N (RR); N (R) S (O) N (RR); SR; N (RR); NO; OC (O) R; N (R) C (O) R; N (R) S (O) R; N (R) S (O) R; N (R) C (O) N (RR); N (R) C (O) OR; OC (O) N (RR) or C1-6alkyl, where C1-6alkyl is optionally substituted with one or more halogen atoms that are the same or different; R, R, R, R, R are independently selected from the group consisting of H; C 1-6 alkyl, wherein C 1-6 alkyl is optionally substituted with one or more halogen atoms that are the same or different; R 1 represents H; And C1-6alkyl, where C1-6alkyl is optionally substituted with one or more R, which
priorityDate 2011-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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