http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2014108240-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7056 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-775 |
| filingDate | 2012-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2014108240-A |
| titleOfInvention | SHORTED TETRANEKTIN-APOLIPOPROTEIN A-I HYBRID PROTEIN CONTAINING ITS LIPID PARTICLE AND THEIR APPLICATIONS |
| abstract | 1. A chimeric protein that has the amino acid sequence of SEQID NO: 01, or a variant thereof having at least 70% sequence identity with respect to the amino acid sequence of SEQID NO: 01.2. Chimeric protein according to claim 1 for use as a medicine. Chimeric protein according to claim 1 for use in the treatment of: - acute coronary syndrome, or - atherosclerosis, or - atherosclerotic plaques in the patient's blood vessels, or - valve stenosis in the patient, or - septic shock, or - angina pectoris, or - myocardial infarction, or - unstable angina, or - stenosis of the arteries, or - diseases of the peripheral arteries (ZPA), or - stenosis of the carotid artery, or - stenosis of the coronary arteries, or - stenosis of the coronary arteries, or - vascular dementia, or - temporary amaurosis. 4. A chimeric protein according to claim 1 for use in: - inducing reverse transport of cholesterol, or - inducing control of plaques, or - removing / resorbing / stabilizing atherosclerotic plaques, or - redistributing cholesterol from the walls of arteries to the liver, or - increasing the number of HDL particles, or - removal of endotoxins. 5. A lipid particle containing a chimeric protein according to claim 1.6. A lipid particle according to claim 5, comprising: a chimeric protein according to claim 1; phosphatidylcholine i-lipid. A lipid particle according to claim 5, characterized in that it contains: a chimeric protein according to claim 1; a first phosphatidylcholine and a second phosphatidylcholine. 8. A lipid particle according to claim 5, characterized in that it contains 1-palmitoyl-2-oleoylphosphatidylcholine and 1,2-dipalmitoylphosphatidylcholine. The lipid particle according to claim 8, characterized in that the molar ratio of 1-palmitoyl-2-oleoylphosphatidylcholine and 1,2-dipalmit |
| priorityDate | 2011-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.