http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2014106611-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-048 |
| filingDate | 2012-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2014106611-A |
| titleOfInvention | HETEROCYCLIC AMIDES DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS |
| abstract | 1. A compound of formula (I) in which n is 1 or 2; one of X and Y is either —N (O) - and the other is —N— or —C (R) -; R is hydrogen or methyl and R is hydrogen, (CC) alkyl, (CC) deuteroalkyl, hydroxymethyl or heterocyclylmethyl or R and R together with the carbon atom to which they are attached form a saturated carbocyclic ring containing from 3 to 6 members; and R is aryl, aryloxy, aryl- (CC) alkyl, heteroaryl or heteroaryloxy, the groups in the aromatic moiety being independently mono-, di-, tri- or tetra-substituted, the substituents being independently selected from the group consisting of (CC) alkyl, (CC) cycloalkyl, (CC) alkoxy, hydroxy- (CC) alkyl, (CC) fluoroalkyl, (CC) fluoroalkoxy, (CC) alkylcarbonyl, cyano, -CONH, halogen and phenoxy; or R represents hydrogen and R and R together with a carbon atom, to which they are attached form an indanyl or tetrahydronaphthyl group, the groups being in aroma Český moiety independently are mono-, di- or tri-substituted, wherein the substituents are independently selected from the group consisting of (C-C) alkyl, (C-C) fluoroalkyl and halogen; and R, R and R are independently hydrogen, (C-C) alkyl, (C-C) cycloalkyl, (C-C) alkoxy, (C-C) fluoroalkyl or halogen; or a salt of such a compound. 2. The compound of formula (I) according to claim 1, wherein n is 1 or 2; one of X and Y is —N— or —N (O) - and the other is —N — or —C (R) -; R is hydrogen and R is hydrogen, (CC) alkyl, (CC) deuteroalkyl or hydroxymethyl or R and R, together with the carbon atom to which they are attached, form a saturated carbocyclic ring containing from 3 to 6 members; and R represents an aryl group which is di- or trisubstituted, with the substituents independently selected |
| priorityDate | 2011-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 303.