http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2014101230-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-284 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2846 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
| filingDate | 2012-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2014101230-A |
| titleOfInvention | GASTRIC RESISTANT PHARMACEUTICAL OR NUTRICEUTIC COMPOSITION WITH RESISTANCE TO ETHANOL |
| abstract | 1. A gastro-resistant pharmaceutical or nutraceutical composition that comprises a core containing a pharmaceutical or nutraceutical active ingredient and a gastro-resistant coating layer on the core, the gastro-resistant coating layer containing at least 30 wt.% (Meth) acrylate copolymer containing polymerized units, from 10 to 40% by weight of acrylic or methacrylic acid, from 10 to 80% by weight of C-CI alkyl ester of acrylic or methacrylic acid, and optionally from 0 to 60% by weight of another vinyl monomer whereby the release of the pharmaceutical or nutraceutical ingredient is not more than 10% in vitro at pH 1.2 after 2 hours in USP medium with or without 20% (v / v) ethanol. 2 . The gastric-resistant pharmaceutical or nutraceutical composition according to claim 1, wherein the gastro-resistant coating layer comprises a (meth) acrylate copolymer containing polymerized units from 10 to 40 wt.% Acrylic or methacrylic acid, from 10 to 50 wt.% Ethyl acrylate, 10 to 80% by weight of C-C1-6 alkyl ester of acrylic or methacrylic acid and optionally from 0 to 20% by weight of methyl methacrylate. 3. The gastro-resistant pharmaceutical or nutraceutical composition according to claim 1, wherein the release of the pharmaceutical or nutraceutical active ingredient is at least 50% in vitro at a pH of 6.8 after 45 minutes in a buffer medium according to USP.4. The gastro-resistant pharmaceutical or nutraceutical composition according to claim 1, wherein the (meth) acrylate copolymer has an average glass transition temperature of from 25 to 80 ° C. Gastro-Resist |
| priorityDate | 2011-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.