| abstract |
1. A swallowable composition containing a compound of structural formula (IIc) in an amount providing an improvement in sweet taste: or its tautomer, salt, solvate and / or its ester, where: A is hydrogen, alkyl, substituted alkyl, heteroalkyl, substituted heteroalkyl, -CN, -OR, -NHOR, NRCOR, -NRR, -NRCOR, -NRCONRR, -NRCSNRR or -NRC (= NH) NRR; R is hydrogen, alkyl, substituted alkyl, arylalkyl, substituted arylalkyl, heteroalkyl, substituted heteroalkyl, heteroalkyl, heteroalkyl substituted heteroarylalkyl; R, R or R are independently hydrogen, lkilom, substituted alkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, acyl, substituted acyl, heteroalkyl, substituted heteroalkyl, heteroaryl, substituted heteroaryl, heteroarylalkyl or substituted heteroarylalkyl; or alternatively R and R or R and R, together with the atoms to which they are attached, form a cycloheteroalkyl or substituted cycloheteroalkyl ring; W is —S—; Y is —C (R) -; Z is —C (R) -; R is hydrogen, alkyl substituted with alkyl, acyl substituted with acyl, heteroalkyl, substituted heteroalkyl, —CN, —NO, —OR, —S (O) R, —OCOR, —NRR, —CONRR or —COR; R is hydrogen, alkyl substituted with alkyl, acyl substituted with acyl, heteroalkyl substituted with heteroalkyl, —CN, —NO, —OR, —S (O) R, —OCOR, —NRR — CONRR or —COR; or alternatively R and R, together with the atoms to which they are attached, form a cycloalkyl, substituted cycloalkyl, cycloheteroalkyl or substituted cycloheteroalkyl ring; h and i are independently 0 or 1; and R, R, R and R are independently hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, and |