http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2013147429-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5123 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-593 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 |
filingDate | 2012-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2015-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2013147429-A |
titleOfInvention | COMPOSITION CONTAINING LIPID NANOPARTICLES AND A CORTICOSTEROID OR DERIVATIVE OF VITAMIN D |
abstract | 1. A pharmaceutical composition comprising a corticosteroid as a therapeutically active ingredient, embedded in the form of a solid solution or dispersion in lipid nanoparticles, said lipid nanoparticles being solid at ambient temperature and comprise about 60-92% by weight of the first lipid with a melting point above a temperature body, said first lipid is a wax selected from the group consisting of esters of C alcohols and Fatty acids, mono-, di- or tri-esters of glycerol and Fatty acids, C fatty alcohols and cholesterol, wherein said lipid nanoparticles additionally contain about 2-25% by weight of a pharmaceutically acceptable surfactant. 2. The composition according to claim 1, in which the first lipid is selected from the group consisting of cetyl palmitate, beeswax, stearyl palmitate, stearyl behenate, glycerol monostearate, glycerol distearate, glycerol dibegenate, glycerol trimyristate, glycerol tripalmitate, trimester oils, hydrogenated coconut oil glycerides, hydrogenated castor oil and cetostearyl alcohol. 3. The composition of claim 1, wherein the surfactant is selected from the group consisting of poloxamers, polysorbates, sugar esters, ethoxylated fatty alcohols or phospholipids. The composition according to PP. 1-4, additionally containing about 1-40%, for example, about 10-30% by weight or about 15-25% by weight, or about 20% by weight of lipid nanoparticles from the second lipid, which is |
priorityDate | 2011-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.