http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2013146524-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H5-04 |
filingDate | 2012-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2015-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2013146524-A |
titleOfInvention | SYNTHESIS OF NEW FUCOSE-CONTAINING HYDROCARBON DERIVATIVES |
abstract | 1. A method of obtaining a compound of formula 1 or a salt thereof, where A is a carbohydrate linker that is a lactosyl residue or that consists of a lactosyl residue and at least one monosaccharide unit selected from the group consisting of: glucose, galactose, N -acetylglucosamine, fucose and N-acetylneuraminic acid; and where R 2 is one of the following anomeric protecting groups: a) —OR, where R 2 is a protecting group removable by catalytic hydrogenolysis, b) —SR, where R is optionally substituted alkyl, optionally substituted aryl or optionally substituted benzyl, c) -NH-C (R '') = C (R '), where each of R' independently represents one of the following electron-withdrawing groups: -CN, -COOH, -COO-alkyl, -CO-alkyl, -CONH, - CONH-alkyl or -CON (alkyl), or where two R'-groups are joined together and form -CO- (CH) -CO- and thus form, together with the carbon atom to which they are attached, a 5-7 membered cycloalkane -1,3-dione, in which any of the methylene groups is optionally substituted with 1 or 2 alkyl groups, and R ″ is H or alkyl, characterized in that the donor of fucosyl of formula 2, where X is selected from the group consisting of: guanosine diphosphatyl residue, lactose residue, azide, fluoride, optionally substituted phenoxy, optionally substituted o pyridinyloxy optionally substituted with 3-oxo-furanyloxy of formula A, optionally substituted 1,3,5-triazinyloxy of formula B, a 4-methylumbelliferyloxy group of formula C, and a group of formula D, wherein R is independently H or alkyl, or two adjacent R 2 groups are group = C (R), where R is independently |
priorityDate | 2011-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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