http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2013145418-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-16 |
| filingDate | 2012-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2013145418-A |
| titleOfInvention | Cycloalkenylaryl derivatives for the inhibition of the transport protein of cholesterol esters |
| abstract | 1. Cycloalkenylaryl derivatives of Formula 1, their isomers, pharmaceutically acceptable salts, hydrates and solvates: where B and B are each independently N or C, while both B and B cannot simultaneously be N, and if one of B and B is N, then R or R is absent, R and R are each independently are H, -F, -OH, -NH, -C (= O) H, -CHOH, -OC-C1-6alkyl, -SC-C1-6alkyl, -CHOS-C1-6alkyl, -NH (C-C1-6alkyl), -NH ( C = O) (C-C1-6alkyl), or, R and R, together with the carbon atoms to which they are bonded, can form a 5- or 6-membered heterocyclic aromatic or non-aromatic cyclic compound having from 1 d about 3 heteroatoms independently selected from the group consisting of N, O, S, and C (= O), wherein the heterocyclic aromatic or non-aromatic cyclic compound may be optionally substituted with R, R is —H, —F, —OH, —C- C1-6alkyl, -OC-C1-6alkyl, R is -H, halogen, -CN, -NO, -C-C1-6alkyl, -C-Salkenyl, -C-Cycloalkyl ,,, -OR, -CHOR, -CHNRR, -SR, - C (= O) R, -COR, -CHRCOR, -C (= O) NRR ,,,,,, -NRR, -NRC (= O) R, -NRCOR ,,,,,,,, -NRC ( = O) NRR, —NRC (= S) NRR, Ar or Het, R and R, together with the carbon atoms to which they are bonded, can form a 5- or 6-membered cycloalkyl or heterocyclic compound having from 0 to 3 heteroato independently selected from the group consisting of N, O, S, and C (= O), wherein the cycloalkyl or heterocyclic compound may be optionally substituted with R, Ar is a C6 monocyclic aromatic compound that is unsubstituted or optionally substituted with one or more substituents selected from the group consisting of halogen, —OH, —NH, —C — C1-6alkyl and —OC — C1-6alkyl, Het is a 5- or 6-membered heterocyclic compound containing from 0 to 2 double bonds and from 1 to 4 heteroatoms, independently selected from the group consisting of N, O, S, C (= O) and |
| priorityDate | 2011-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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