http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2013145240-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2013-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2013145240-A |
| titleOfInvention | METHOD FOR FORECASTING FAST VIROLOGICAL RESPONSE IN PATIENTS WITH CHRONIC HEPATITIS WITH |
| abstract | A method for predicting a rapid virological response in patients with chronic hepatitis C, including determining the allelic variant of the IL-28B gene in patients and conducting immunological testing, characterized in that, in the presence of the rsl2979860CC / rs8099917TT allele, the Immuno Prediction Factor 1 (KIP1) is calculated by the formula: KIP1 = 2.774- 0.833 · [CD3 +] - 0.016 · [CD4 +] - 0.063 · [CD8 +] - 0.525 · [CD19 +], where [CD3 +] is the absolute content of CD3 + cells in 1 liter of blood, [CD4 +] is the absolute content of CD3 + / CD4 + cells in 1 l of blood, [CD8 +] - absolute content of CD3 + / CD8 + cells in 1 l of blood, [CD19 +] - absolute content CD19 + cells in 1 liter of blood, with a value of <1.5 predict the development of a rapid virological response to therapy with pegylated interferon α and ribavirin, and> 1.5 - its absence; in the presence of any other allelic variant, CIP2 is calculated according to the formula: CIP2 = 3.994 + 0.014 · [CD56 + / ki-67 +] - 0.408 · [CD25hi] -0.69 · [CD25hi / FoxP3 +], where [CD56 + / ki-67 + ] - the percentage of CD16 + / CD56 + / ki-67 + cells among blood lymphocytes, [CD25hi] - the percentage of CD3 + / CD25high cells among blood lymphocytes, [CD25hi / FoxP3 +] - the percentage of CD3 + / CD25high / FoxP3 + cells among blood lymphocytes, with a value of < 3.0 predict the development of a rapid virological response to therapy with pegylated interferon α and ribavirin, and> 3.0 - its absence. |
| priorityDate | 2013-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.