http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2013145013-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-605 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-26 |
| filingDate | 2012-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2013145013-A |
| titleOfInvention | NEW GLUCAGON ANALOGUES |
| abstract | 1. Derived glucagon peptide with the formula [I]: containing a Deputy attached to the nitrogen atom of the side chain amino acids at positions X, X, X, X, X, X, X, and / or X specified glucagon peptide, where the specified Deputy has the formula II : where Y, Y, Y, Y, Y, Y, Y, Y, Y, Y, and Y are individually absent or individually are amino acids i, ii, iii or iv that have the stereochemistry L or D or structure v :, and Y is absent or represents a C-acyl group or a succinoyl group, provided that the substituent of formula II contains from three to ten five negatively charged groups, or a pharmaceutically acceptable salt, amide or carboxylic kislota.2. The glucagon peptide derivative of claim 1, wherein: Y is absent or is an amino acid such as, but not limited to Arg, ε-Lys or Gly; Y, Y, Y, Y, Y, Y, Y, Y, Y, or Y individually absent or individually represent amino acids i or ii ;; and Y is absent or represents the structure of formulas vi, vii, viii, ix, x or xi: .3. The glucagon peptide derivative of claim 2, wherein: Y is absent or is an amino acid Arg, ε-Lys or Gly; Y, Y, Y, Y, Y, Y, Y, Y, Y, or Y are individually absent or individually are i or ii ;; and Y is absent or represents the structure of formulas vi, vii, viii, ix, x or xi: .4. The glucagon peptide derivative of claim 1, wherein said substituent is attached to the side chain of an amino acid at the position of the indicated glucagon peptide. The glucagon peptide derivative of claim 4, wherein X is Lys. 6. The glucagon peptide derivative of claim 1, wherein said glucagon peptide contains up to 15 substitutions of amino acid residues and where: X is Ser, Aib, Thr, A |
| priorityDate | 2011-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 149.