| abstract |
1. The compound of formula I: or a pharmaceutically acceptable salt thereof, wherein, independently in each case: R is H, C-C1-6alkyl, C-Cycloalkyl, halogen, CN, NRSOR, SOR, SR, SOR, NRCOR, NRCOR, CON (R ), SON (R), CF, heterocycloalkyl, or unbranched, branched or cyclic (CC) -R, where up to two CH groups can be replaced by O, CO, S, SO, SO, or NR, or two R together form an oxo group, or 3- 7-membered fused cycloalkyl ring, or 3-7-membered spirocyclic ring; R is H, C-C1-6alkyl, halogen, C-Haloalkyl, CN, OH, SOR, SR, SOR, COR, CON (R), COR, SON (R), CF, CHF or unbranched st, branched or cyclic (CC) -R, where up to two CH groups can be replaced by O, CO, S, SO, SO, CF or NR; R is H, C-C1-6alkyl, C-Cycloalkyl, COR, COR, СОН, CON (R), CF, CHCF, CHCHF, or unbranched, branched or cyclic (CC) -R, where up to two CH groups can be replaced by O, CO, S, SO, SO, CF or NR; R is H, C-C1-6alkyl, halogen, C-Cycloalkyl, where up to two CH groups can be replaced by O, CO, S, SO, SO, or NR, or two R together form a fused 3-7 membered cycloalkyl ring; R is H, C-C1-6alkyl, CF, C-Cycloalkyl , fluoroalkyl, aryl, heteroaryl, or non-branched a branched, branched or cyclic (CC) -R, where up to two CH groups can be replaced by O, CO, S, SO, SO or NR, or two R form together with the atoms to which they are attached, a ring; R represents H, CF, COR , OH, aryl, heteroaryl, C-Cycloalkyl, heterocycloalkyl, N (R), NRCOR, CON (R), CN, halogen or SOR; R is H, C-C1-6alkyl, aryl, heteroaryl, C-Cycloalkyl or heterocycloalkyl; A is an optionally substituted aryl, heteroaryl or heterocyclyl; m is an integer from 0 to 4 inclusive; n is an integer from 0 to 3 inclusive; and is equal to the integer � |