http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2013139247-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-455 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-455 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D245-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5517 |
filingDate | 2012-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2015-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2013139247-A |
titleOfInvention | FLUMAZENIL COMPLEXES CONTAINING THEIR COMPOSITIONS AND THEIR APPLICATIONS |
abstract | 1. Pharmaceutically acceptable complex of ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo [1,5-a] [1,4] benzodiazepine-3-carboxylate or its salt and complexing agent an agent or a derivative thereof, provided that the complexing agent is selected from the group consisting of: nicotinamide, sodium nicotinate, sodium benzoate, sodium hydroxybenzoates, sodium salicylate, sodium gentisate, gentisic acid ethanolamide, sodium toluates, sodium aminobenzoate, sodium anthranilate, sodium butyl monoglycol sulfate resorcinol. 2. The pharmaceutically acceptable complex according to claim 1, characterized in that the complexing agent is nicotinamide or a derivative thereof. The pharmaceutically acceptable complex according to claim 1, characterized in that the ratio of complexing agent: flumazenil is in the range from 1: 1 to 2: 1.4. The pharmaceutically acceptable complex according to claim 1, which is a complex of flumazenil and nicotinamide. A pharmaceutical composition comprising the flumazenil complex according to any one of claims 1 to 4 and a pharmaceutically acceptable carrier. The pharmaceutical composition according to claim 5, characterized in that the composition has a form selected from the group consisting of: pills, tablets, chewable tablets, coated tablets, granules, capsules, hard or soft gelatine capsules, aqueous solution, alcohol solution, oil solution, syrup, emulsion, suspension, troches, suppository, injection or infusion solution, ointment, infusion, cream, lotion, powder, spray, transdermal therapeutic systems, nose spray, spray, aerosol mixture, microcapsules, implants, ste zhnya filled and plastyrya.7. Pharmaceutical |
priorityDate | 2011-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 160.