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filingDate 2011-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2015-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2013129206-A
titleOfInvention COMPOSITIONS OF HYALURONIC ACID STABILIZED AGAINST THE DESTRUCTIVE ACTION OF HEAT OR ENZYMES
abstract 1. The use of additives to stabilize hyaluronic acid in the form of an aqueous composition against the damaging effects of heat or enzymes such as hyaluronidase, where the specified additive contains one or more polysaccharides having a molecular weight equal to or greater than 20,000 Da, and solubility in water, according to at least equal to or greater than 1 g / l, the total concentration of the indicated polysaccharide or polysaccharides and hyaluronic acid in the composition, giving a viscosity of at least 500 cP, characterized in that the polysaccharide is selected from gellan gum, carrageenans from algae, xyloglucan from tamarind seeds and xanthan gum, in pure form or mixed with each other. 2. The use according to claim 1, characterized in that said composition is suitable for intraarticular, intradermal or intraocular administration to humans or animals. The use according to claim 1, characterized in that said hyaluronic acid has a molecular weight equal to or greater than 2 · 10 Da. The use according to claim 1, characterized in that said hyaluronic acid and said polysaccharide, in pure form or mixed, have mass ratios ranging from 1:10 to 10: 1, respectively. An aqueous composition of hyaluronic acid having a molecular weight equal to or greater than 2 · 10 Da, which contains, as an additive to stabilize against the damaging effects of heat or enzymes such as hyaluronidase, at least one polysaccharide having a molecular weight of more than 20,000 Yes and solubility in water, at least equal to or greater than 1 g / l, a composition having a viscosity of at least 500 cP, characterized in that the polysaccharide
priorityDate 2010-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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