http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2013127593-A

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filingDate 2011-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2015-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2013127593-A
titleOfInvention QUICKLY DISPERSABLE GRANULES, ORAL DECOMPOSITION TABLETS AND METHODS
abstract 1. A pharmaceutically acceptable, fast-dispersing composition in the form of microgranules with a median particle size in the range of from about 100 microns to about 300 microns, containing at least one sugar alcohol, saccharide or mixture thereof, at least one super-disintegrant and at least one multifunctional additive. . A fast-dispersing composition in the form of microgranules with a median particle size in the range from about 100 microns to about 300 microns, obtained by simple and quick granulation of a powder mixture containing: at least one sugar alcohol, saccharide or a mixture thereof, at least one super-disintegrant and at least one one pharmaceutically acceptable multifunctional additive in a ratio of approximately 88-98 (sugar alcohol): 1-10 (baking powder): 1-3 (multifunctional additive), in a fluidized bed granulator without c the need to grind wet granular products and / or prolonged grinding of dry granular product. 3. The fast-dispersing composition in the form of microgranules according to claim 1 or 2, wherein at least one sugar alcohol, saccharide or mixture thereof, at least one super-disintegrant and at least one multifunctional additive are present in a ratio of approximately 88-96 (sugar alcohol): 1-10 (baking powder): 1-3 (multifunctional additive) .4. A fast-dispersing composition in the form of microgranules according to claim 1 or 2, wherein the sugar alcohol is selected from the group consisting of mannitol, xylitol a, and a mixture thereof, the saccharide is selected from the group consisting of lactose, sucrose, fructose, and a mixture thereof. The fast-dispersing composition in the form of microgranules according to claim 1 or 2, where superrazry
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