http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2013125756-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 |
filingDate | 2011-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2014-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2013125756-A |
titleOfInvention | SOLID FORMS ) -2,2,2-TRIFTORETOXY) PYRIMIDIN-4-IL) Phenyl) PROPANIC ACID |
abstract | 1. A crystalline compound which is (S) -2-amino-3- (4- (2-amino-6 - ((R) -1- (4-chloro-2- (3-methyl-1H-pyrazole -1-yl) phenyl) -2,2,2-trifluoroethoxy) pyrimidin-4-yl) phenyl) propanoic acid or its salt. 2. Crystalline (S) -2-amino-3- (4- (2-amino-6 - ((R) -1- (4-chloro-2- (3-methyl-1H-pyrazol-1-yl) phenyl) -2,2,2-trifluoroethoxy) pyrimidin-4-yl) phenyl) propanoic acid, the DSC thermogram of which has a peak at about 126 ° C. 3. A crystalline compound that is (S) -2-amino-3- (4- (2-amino-6 - ((R) -1- (4-chloro-2- (3-methyl-1H-pyrazole- 1-yl) phenyl) -2,2,2-trifluoroethoxy) pyrimidin-4-yl) phenyl) propanoic acid. 4. The crystalline compound according to claim 3, which is anhydrous. The crystalline compound according to claim 4, which has a melting point of about 234 ° C and / or a peak in the DSC thermogram at about 238 ° C. The crystalline compound according to claim 5, which has a powder X-ray diffraction pattern including peaks at one or more 2Θ angles of about 9.2, 15.9, 16.8, 18.4, 19.8 and / or 20 , 8 degrees. 7. The crystalline compound according to claim 3, which is a hydrate. A crystalline compound according to claim 7, which has a melting point of about 218 ° C and / or a peak in the DSC thermogram at about 230 ° C. A compound according to claim 7, which has a powder X-ray diffraction pattern including peaks at one or more 2Θ angles of about 8.7, 9.1, 13.4, 18.3 and / or 20.2 degrees. . The crystalline compound according to claim 4, which has a melting point of about 228 ° C and / or a peak in the DSC thermogram at about 233 ° C. 11. The crystalline compound according to claim 4, which has a powder X-ray diffraction pattern including peaks at one or more 2Θ angles of about 8.7, 9.5, |
priorityDate | 2010-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.