http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2013125756-A

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filingDate 2011-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2014-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2013125756-A
titleOfInvention SOLID FORMS ) -2,2,2-TRIFTORETOXY) PYRIMIDIN-4-IL) Phenyl) PROPANIC ACID
abstract 1. A crystalline compound which is (S) -2-amino-3- (4- (2-amino-6 - ((R) -1- (4-chloro-2- (3-methyl-1H-pyrazole -1-yl) phenyl) -2,2,2-trifluoroethoxy) pyrimidin-4-yl) phenyl) propanoic acid or its salt. 2. Crystalline (S) -2-amino-3- (4- (2-amino-6 - ((R) -1- (4-chloro-2- (3-methyl-1H-pyrazol-1-yl) phenyl) -2,2,2-trifluoroethoxy) pyrimidin-4-yl) phenyl) propanoic acid, the DSC thermogram of which has a peak at about 126 ° C. 3. A crystalline compound that is (S) -2-amino-3- (4- (2-amino-6 - ((R) -1- (4-chloro-2- (3-methyl-1H-pyrazole- 1-yl) phenyl) -2,2,2-trifluoroethoxy) pyrimidin-4-yl) phenyl) propanoic acid. 4. The crystalline compound according to claim 3, which is anhydrous. The crystalline compound according to claim 4, which has a melting point of about 234 ° C and / or a peak in the DSC thermogram at about 238 ° C. The crystalline compound according to claim 5, which has a powder X-ray diffraction pattern including peaks at one or more 2Θ angles of about 9.2, 15.9, 16.8, 18.4, 19.8 and / or 20 , 8 degrees. 7. The crystalline compound according to claim 3, which is a hydrate. A crystalline compound according to claim 7, which has a melting point of about 218 ° C and / or a peak in the DSC thermogram at about 230 ° C. A compound according to claim 7, which has a powder X-ray diffraction pattern including peaks at one or more 2Θ angles of about 8.7, 9.1, 13.4, 18.3 and / or 20.2 degrees. . The crystalline compound according to claim 4, which has a melting point of about 228 ° C and / or a peak in the DSC thermogram at about 233 ° C. 11. The crystalline compound according to claim 4, which has a powder X-ray diffraction pattern including peaks at one or more 2Θ angles of about 8.7, 9.5,
priorityDate 2010-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 40.