http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2013114362-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-36143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-36171 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16134 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 |
| filingDate | 2011-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2013114362-A |
| titleOfInvention | PEGILATED LIPOSOMES FOR THE DELIVERY OF ENCODING IMMUNOGEN RNA |
| abstract | 1. A liposome in which an RNA encoding an immunogen of interest is encapsulated, wherein the liposome contains at least one lipid that includes a polyethylene glycol moiety such that the polyethylene glycol is present on the outer surface of the liposome, wherein the average molecular weight of the polyethylene glycol is from 1 kDa to 3 kDa. 2. The liposome according to claim 1, containing PEG-DMG and / or a lipid of the formula (X): where: Z is a component in the form of a hydrophilic head group selected from PEG and polymers based on poly (oxazoline), poly (ethylene oxide), poly (vinyl oxide) alcohol), poly (glycerol), poly (N-vinylpyrrolidone), poly [N- (2-hydroxypropyl) methacrylamide] and poly (amino acids), where the polymer may be linear or branched, and where the polymer may be optionally substituted; Z is polymerized n subunits; n denotes the number average polymerization from 10 to 200 Z units (and can optimize I for various groups Z); L is optionally substituted with a C alkylene or C heteroalkylene linker, including zero, one or two of an ether (e.g. -O-), an ester (e.g. -C (O) O-), a succinate (e.g., - O (O) C-CH-CH-C (O) O-)), carbamate (e.g. -OC (O) -NR'-), carbonate (e.g. -OC (O) O-), urea (e.g. , -NRC (O) NR -), an amine (e.g., -NR'-), an amide (e.g. -C (O) NR'-), an imine (e.g. -C (NR ') -), a thioether (e.g. , -S-), xanthate (e.g., -OC (S) S-) and phosphodiester (e.g., -OP (O) O-), where R 'is independently selected from -H, -NH-, -H, -O -, -S-, phosphate or optionally substituted Calkylene; X and X independently selected from carbon or a heteroatom selected from -NH-, -O-, -S- or phosphate; A and A are independently selected from C1-6alkyl, C1-6alkenyl and C1-6alkynyl, where A and A may be the same or different, or A and A at |
| priorityDate | 2010-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.