http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2013103079-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-443 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4433 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4436 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-00 |
| filingDate | 2011-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2013103079-A |
| titleOfInvention | HETEROCYCLIC COMPOUNDS OF BENZODIOXOL OR BENZODIOXEPIN AS PHOSPHODYESTERASE INHIBITORS |
| abstract | 1. The compound of general formula I, each of m and n, independently represents 0 or 1; R and R, together with the carbon atom to which they are attached, form a heterocyclic ring containing one or two heteroatoms selected from oxygen, sulfur, -S (O ) - and -S (O) -; R is -CHF, -CF, -OCHF, -OCF, -SCHF or -SCF; X is a bond, -CH- or -NH-; A is aryl, cycloalkyl, cycloalkenyl , arylalkyl, heteroaryl, heteroarylalkyl, heterocycloalkyl or heterocycloalkenyl, optionally substituted with one or more identical or different estitelyami selected from R; and R is hydrogen, amino, thioxo, alkyl, haloalkyl, hydroxyalkyl, alkoxy, haloalkoxy, halogen, oxo, thia or hydroxy; or a pharmaceutically acceptable salt, hydrate or solvate thereof. 2. The compound of claim 1, wherein X is —CH— or —NH — .3. A compound according to claim 1 or 2 of general formula IIa wherein m, n, R, R and R are as defined in claim 1.4. The compound according to claim 1, where both m and n are equal to 0.5. The compound according to claim 1, where both m and n are equal to 1.6. A compound according to claim 1, wherein R is —OCHF or —OCF. The compound of claim 6, wherein R1 is -OCHF. A compound according to claim 1, wherein R is —SCHF or —SCF. A compound according to claim 1, wherein R and R, together with the carbon atom to which they are attached, form a 4-, 5- or 6-membered heterocyclic ring. The compound of claim 9, wherein the heterocyclic ring is tetrahydropiran, oxetane, [1,3] dioxolane, [1,3] dioxane, tetrahydrothiopyran, tetrahydrothiopyran-1,1-dioxide, tetrahydrothiopyran-1-oxide, tetrahydrothiophene, [1, 3] -dithian, thietane, [1,3] -dithian-1,3-dioxide, thietan-1-oxide, or thiethane-1,1-dioxide. 11. The compound according to claim 9, where the heterocyclic ring contains odi |
| priorityDate | 2010-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 80.