http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2012157041-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14 |
filingDate | 2011-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2014-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2012157041-A |
titleOfInvention | CHEMICAL SYNTHESIS AND ANTITUMOR AND ANTIMETASTATIC DUAL ACTION CONJUGATE EFFECTS |
abstract | 1. At least one active pharmaceutical ingredient selected from conjugates of formula I, and its pharmaceutically acceptable soligide A, is phenyl, B acetoxy; when A is tert-butoxy, B is hydroxy; n = 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12; where X is selected from C1-6alkyl, C1-6alkylene and C1-6alkyl containing a heteroatom, wherein said heteroatom is independently selected from oxygen, sulfur and nitrogen; or X is a single bond in such a way that M is directly bonded to acyl; where M is selected from aryl and heteroaryl; where R is selected from hydrogen, substituted or unsubstituted straight or branched C1-6 alkyl, hydroxy, substituted or unsubstituted straight or branched C1-6 alkoxy, sulfhydryl, substituted or unsubstituted unbranched or branched C1-6 alkyl, C1-6 alkoxy, amino; substituted or unsubstituted unbranched or branched C1-6 alkylamino, including monoalkylamino or dialkylamino; an aldehyde group, substituted or unsubstituted straight or branched C1-6 alkyl, carboxyl, substituted or unsubstituted straight or branched C1-6 alkyl, carbamoyl, substituted or unsubstituted straight or branched C1-6 alkyl, Salken, halogen, nitro and cyano; the substituted C-Unbranched or branched chain group described herein is selected from hydroxyl, sulfhydryl, amino, aldehyde group, carboxyl, carbamoyl, halogen, nitro and cyano. 2. At least one active pharmaceutical ingredient according to claim 1, characterized in that n = 2, 3, 4, 5, 6, 7, 8, 9, or 10.3. At least |
priorityDate | 2010-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 127.