http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2012151498-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2121-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-433 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4196 |
filingDate | 2011-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2014-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2012151498-A |
titleOfInvention | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURONS OR NEURODEGENERATION |
abstract | 1. A pharmaceutical composition for inhibiting neuronal apoptosis or neurodegeneration, comprising: a therapeutically effective amount of a compound selected from the group consisting of a substituted azole derivative represented by formula 1, pharmaceutically acceptable salts thereof, substituted azole derivative isomers, substituted azole derivative solvates, substituted derivative hydrates azole and their combinations; and a pharmaceutically acceptable carrier: Formula I wherein R is selected from the group consisting of a substituted or unsubstituted C-Carylalkyl group, a substituted or unsubstituted C-Ceteroarylalkyl group, and a substituted or unsubstituted, linear, C-Calkyl group; Y is selected from the group consisting of O and -NR; R is at least one selected from the group consisting of H and a linear or branched C-C1-6 alkyl group; R is selected from the group consisting of H and halogen; A is selected from the group consisting of N, O and S; B is C or N; Z is selected from the group consisting of substituted oh or unsubstituted heterocyclic group, carbamate, -OC (= O) NRR, NH, NRR, NC (= NH) NHi -NC (= O) NH; each of R independently is selected from the group consisting of H; C-C1-6 alkyl unsubstituted or substituted by at least one substituent selected from the group consisting of NH and NRR; a heterocyclic ring unsubstituted or substituted with Ci-Ci; or R and R together can form a 5- or 7-membered heterocyclic ring unsubstituted or substituted with C-C 1-6 alkyl; each of R and R is independently selected from the group consisting of H; C-Salken; C-Calkine; and linear or branched C-C1-6 alkyl, unsubstituted or substituted by at least one substituent selected from the group consisting of-OH, -C (O) |
priorityDate | 2010-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.