http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2012139082-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4965 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-182 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-65 |
| filingDate | 2011-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2012139082-A |
| titleOfInvention | METHODS FOR PRODUCING CYCLOPROPYLAMIDE DERIVATIVES AND INTERMEDIATE COMPOUNDS RELATED TO THEM |
| abstract | 1. The compound of formula Ia or its pharmaceutically acceptable salt: 2. A method of obtaining a compound according to claim 1, comprising reacting a compound of formula IX; with a base and peroxide; and then the interaction of the resulting mixture with an acidic solution. 3. The method according to claim 2, where the compound of formula IX is obtained by a method comprising reacting a compound of formula VIII: with a metal, a metal cyanide and a catalyst, IX represents Cl, Br or I.4. The method according to claim 3, where the compound of formula VIII is obtained by a method comprising reacting a compound of formula VII: with a mixture of the first base and tricalkylphosphonoacetate; and then reacting the resulting mixture with a second base. 5. The method of claim 4, wherein the compound of formula VII is prepared by a process comprising reacting a compound of formula VI: with a base; and LG is Cl, Br, I, tosylate, brosylate, nosylate, mesylate or triflate. 6. The method of claim 5, wherein the compound of formula VI is prepared by a process comprising reacting a compound of formula V: with a reducing agent and a chiral oxazaborolidine. A method of obtaining a compound of formula Ib or a pharmaceutically acceptable salt thereof: comprising reacting a compound of formula Ia: with (1) an activating agent and (2) a compound of formula IVa or a suitable salt thereof: 8. The method according to claim 7, wherein said activating agent is 1,1'-carbonyldiimidazole. The method of claim 7, wherein the compound of formula IVa or a suitable salt thereof is prepared by a process comprising reacting a compound of formula IIIa: with an acid. The method of claim 9, wherein the compound of formula IIIa is prepared by a process comprising reacting a compound of formula IIa: with cyclobutanone and a reducing agent. A method of obtaining a compound of formula Ic or e� |
| priorityDate | 2010-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.