http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2012137499-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-732 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-734 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
filingDate | 2011-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2014-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2012137499-A |
titleOfInvention | PHARMACEUTICAL COMPOSITION FOR TREATMENT AND / OR PREVENTION OF CANCER |
abstract | 1. A pharmaceutical composition for treating and / or preventing cancer, comprising an antibody or fragment thereof as an active ingredient that is immunologically reactive to the incomplete CAPRIN-1 polypeptide, wherein CAPRIN-1 is any of the sequences numbered by even numbers among the sequences SEQ ID NO: 2-30, and wherein the partial polypeptide contains the amino acid sequence shown in SEQ ID NO: 37, or an amino acid sequence having 80% or higher identity p amino acid sequence sequences of SEQ ID NO: 37.2. The pharmaceutical composition according to claim 1, wherein the cancer is breast cancer, brain tumor, leukemia, lymphoma, lung cancer, mastocytoma, kidney cancer, cervical cancer, bladder cancer, esophageal cancer, stomach cancer or colon and colon cancer .3. The pharmaceutical composition of claim 1, wherein the antibody is a monoclonal antibody or a polyclonal antibody. The pharmaceutical composition according to any one of the preceding claims, wherein the antibody is a human antibody, a humanized antibody, a chimeric antibody, a single chain antibody, or a bispecific antibody. An antibody having immunological reactivity to a polypeptide that contains the amino acid sequence shown in SEQ ID NO: 37, or an amino acid sequence having 80% or higher sequence identity with the amino acid sequence of SEQ ID NO: 37.6. The antibody according to claim 5, which has cytotoxic activity directed against a cancer cell expressing a CAPR protein |
priorityDate | 2010-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.