http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2012136587-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate | 2012-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2012136587-A |
| titleOfInvention | LIGAND CONJUGATES WITH MULTIPLE MEDICINES |
| abstract | 1. A drug delivery conjugate that binds a receptor, comprising: (a) a receptor binding group; (b) a polyvalent linker; and (c) two or more drugs, or their analogues or derivatives; where the receptor-binding group is covalently linked to the polyvalent linker; two or more drugs, or their analogues or derivatives, are covalently linked to the polyvalent linker; The polyvalent linker includes one or more components selected from the group consisting of spacer linkers that release linkers and linkers with a heteroatom, and combinations thereof. 2. A drug delivery conjugate binding a vitamin receptor of the formula: where (L) is selected from the group consisting of (l), (l) and (l) and combinations thereof; where (l) is a release linker, (l) is a spacer linker, and (l) is a heteroatom linker; (B) is a vitamin-binding receptor group, n is an integer greater than 1, and (D ) in each case, is an independently selected drug, or its analogue or derivative; each of a, b, and c independently represents 0, 1, 2, 3, or 4.3. A drug delivery conjugate binding a vitamin receptor of the formula: wherein (L) is selected from the group consisting of (l) and (l), and combinations thereof; where (l) represents a spacer linker and (l) represents a linker with a heteroatom; and each of a and b independently represents 0, 1, 2, 3, or 4; and (B) represents a binding receptor for the vitamin group, n represents an integer of more than 1, and (D) in each case represents not� |
| priorityDate | 2005-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.