http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2012136578-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 |
| filingDate | 2012-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2012136578-A |
| titleOfInvention | PHARMACEUTICAL COMPOSITIONS BASED ON N-CARBAMOIL-METHYL-4-Phenyl-2-Pyrrolidone |
| abstract | 1. A pharmaceutical composition based on N-carbamoyl-methyl-4-phenyl-2-pyrrolidone (Phenotropil ™), in which N-carbamoyl-methyl-4-phenyl-2-pyrrolidone is about 90% by weight of the composition; lactose monohydrate, in an amount of 3-10% by weight of the composition; carboxymethyl cellulose in an amount of 2-5% by weight of the composition; polyvinylpyrrolidone in an amount of 2-5% by weight of the composition; and a stearic acid salt in an amount of 0.2-2.0% by weight of the composition. 2. The composition according to claim 1, characterized in that N-carbamoyl-methyl-4-phenyl-2-pyrrolidone is the levorotatory isomer of N-carbamoyl-methyl-4-phenyl-2-pyrrolidone. A composition according to claim 1, characterized in that N-carbamoyl-methyl-4-phenyl-2-pyrrolidone is the dextrorotatory isomer of N-carbamoyl-methyl-4-phenyl-2-pyrrolidone. A composition according to claim 1, characterized in that N-carbamoyl-methyl-4-phenyl-2-pyrrolidone is a mixture of racemates of N-carbamoyl-methyl-4-phenyl-2-pyrrolidone. The composition according to claim 1, characterized in that it may further comprise starch. The composition according to claim 1, characterized in that it is made in the form of tablets. N-carbamoyl-methyl-4-phenyl-2-pyrrolidone-based pharmaceutical composition comprising N-carbamoyl-methyl-4-phenyl-2-pyrrolidone, lactose monohydrate, carboxymethyl cellulose, polyvinyl pyrrolidone and a stearic acid salt in which N- carbamoyl-methyl-4-phenyl-2-pyrrolidone in an amount of 70-80% by weight of the composition. 8. A composition according to claim 7, wherein N-carbamoyl-methyl-4-phenyl-2-pyrrolidone is the levorotatory isomer of N-carbamoyl-methyl-4-phenyl-2-pyrrolidone. The composition according to claim 7, characterized in that the N-carbamoyl-methyl-4-phenyl-2-pyrrolidone is a dextrorotatory isomer of N-carbamoyl |
| priorityDate | 2012-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.