| abstract |
1. The compound of formula I: where R is H and R is CC-alkyl, optionally substituted with 1-3 substituents independently selected from the group consisting of: halogen, hydroxy, cyano, azido, CC-haloalkyl, CC-alkoxy, CC-haloalkoxy, CC- alkoxycarbonyl, CC-alkylcarbonyl, amine, CC-alkylamine, CC-dialkylamine, CC-alkylsulfonyl, CC-alkylsulfonylamino, aminocarbonyl, aminosulfonyl, carbocyclyl and Het; or R is carbocyclyl or Het; or R and R, together with the nitrogen atom to which they are attached, mean a saturated cyclic amine with 3-6 atoms in the cycle; where carbocyclyl, Het or cyclic amine are optionally substituted with 1-3 substituents independently selected from the group consisting of halogen, hydroxy, cyano, azido, CC-alkyl, CC-haloalkyl, CC-alkoxy, CC-haloalkoxy, CC-alkoxycarbonyl, CC-alkylcarbonyl, amine, CC-alkylamine, CC-dialkylamine, CC-alkylsulfonyl, CC-alkylsulfonylamino, aminocarbonyl, aminosulfonyl, Rx CC-alkylene (where Rx is H, CC-alkyl or CC-haloalkyl), phenyl, benzyl or and CC-cycloalkyl-CC-alkylene; where the phenyl, benzyl or cycloalkyl moiety is optionally substituted with 1-3 substituents independently selected from the group consisting of halogen, CC-alkyl, CC-haloalkyl or CC-alkoxy); R and R are independently selected from the group including H, halogen, CC-alkyl, CC-haloalkyl, CC-alkoxy, or R and R, together with the carbon atom to which they are attached, form CC-cycloalkyl; R is CC-alkyl optionally substituted with 1-3 substituents independently selected from halogen, CC-haloalkyl, CC-alkoxy, CC-halogen nalkoksi; or R 1 is C 1-6 alkyl with at least 2 chloro or 3 fluoro substituents; or R is C-C-cycloalkylmethyl optional |