http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2012126112-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2010-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2012126112-A |
| titleOfInvention | COMPOUND, SOME ITS NEW FORMS, PHARMACEUTICAL COMPOSITIONS ON ITS BASIS AND METHODS FOR PRODUCING AND APPLICATION |
| abstract | 1. N- (2- (Dimethylamino) ethyl) -1- (3 - ((4 - ((2-methyl-1H-indol-5-yl) oxy) pyrimidin-2-yl) amino) phenyl) methanesulfonamide / or a pharmaceutically acceptable salt thereof. 2. A pharmaceutical composition comprising at least one pharmaceutically acceptable carrier and N- (2- (dimethylamino) ethyl) -1- (3 - ((4 - ((2-methyl-1H-indol-5-yl) oxy) pyrimidine- 2-yl) amino) phenyl) methanesulfonamide / or a pharmaceutically acceptable salt thereof. 3. Form I N- (2- (dimethylamino) ethyl) -1- (3 - ((4 - ((2-methyl-1H-indol-5-yl) oxy) pyrimidin-2-yl) amino) phenyl) methanesulfonamide. 4. Form I according to claim 3, characterized in that Form I is substantially free of the amorphous form of the compounds of Formula A, and also substantially free of Form II of the compounds of Formula A.5. The method of obtaining Form I N - (- (2- (dimethylamino) ethyl) -1- (3 - ((4 - ((2-methyl-1H-indol-5-yl) oxy) pyrimidin-2-yl) amino) phenyl) methanesulfonamide, including: (1) mixing N- (2- (dimethylamino) ethyl) -1- (3 - ((4 - ((2-methyl-1H-indol-5-yl) oxy) pyrimidin-2- il) amino) phenyl) methanesulfonamide with at least one organic solvent in which this substance is dissolved, and then heating the mixture to reflux to obtain a solution; (2) cooling the solution to room temperature; and (3) isolating the Form I N- (2- (dimethylamino) ethyl) -1- (3 - ((4 - ((2-methi -1H-indol-5-yl) oxy) pyrimidin-2-yl) amino) phenyl) methanesulfonamide 6. The method according to claim 5, characterized in that at least one organic solvent in which the substance is dissolved is selected from alcohols and aprotic solvents. 7. The method according to claim 5, characterized in that the alcohols are selected from methanol, ethanol and isopropanol. 8. The method according to claim 5, characterized in that the aprotic solvents are selected from acetone, acetonitrile, ethyl acetate |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2712187-C2 |
| priorityDate | 2009-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.