http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2012125626-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-1353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3878 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3834 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0619 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0663 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0797 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-19 |
| filingDate | 2010-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2012125626-A |
| titleOfInvention | IMPLANT COMPOSITION FOR REGENERATION OF NERVOUS TISSUE, METHOD OF ITS PRODUCTION AND ITS APPLICATION |
| abstract | 1. A biocompatible, biodegradable implant composition for nerve tissue regeneration, containing the following components: a) a gel framework formed from a liquid containing isolated platelets and an activating agent containing calcium chloride, with or without thrombin, b) nerve growth factor selected from BDNF , NGF, retinoic acid and combinations thereof, and a culture of at least 50,000 progenitor stem cells. The biocompatible, biodegradable implant composition according to claim 1, wherein the activating agent can be provided in a separate form from the platelet-containing liquid to form an in situ gel framework. The biocompatible, biodegradable implant composition according to claim 1, wherein the platelet-containing liquid is selected from a platelet-rich plasma and a platelet-poor plasma. The biocompatible, biodegradable implant composition according to claim 3, wherein the platelet-containing liquid is platelet-poor plasma. The biocompatible, biodegradable implant composition according to claim 4, further comprising exogenously added platelet growth factors. The biocompatible, biodegradable implant composition according to claim 3, where a) is a gel framework formed from platelet-rich fluid and calcium chloride in an amount in the range of 25-50 μmol / L. 7. A biocompatible, biodegradable implant composition, where a) additionally includes thrombin in an amount in the range of 0.01-5 IU / ml. 8. A biocompatible, biodegradable implant composition according to any one of claims 6 or 7, wherein b) is a combination of BDNF, NGF and retinoic acid. Biocompatible, biodegradable implant composition |
| priorityDate | 2009-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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